ClassXInteractive Lecture Streaming

This is part 1 of lecture 1. The professors briefly introduce themselves and the course. Professor Cegelski continues by discussing proteins, particularly their structure and folding.

This is part 2 of lecture 1. Professor Cegelski continues by discussing proteins, particularly their structure and folding.

In this lecture, Professor Cegelski discusses the process of protein purification. The lecture covers many of the techniques that would be used in protein purification, the experiments to monitor the purification...

In this lecture, Professor Cegelski discusses three major techniques for studying proteins. She begins with an introduction to mass spectrometry, including MALDI and other methods used for proteins. X-ray...

Professor Cegelski discusses the basics of DNA and RNA. The molecular structure of the bases and the nucleic acids are explained. The major processes of nucleic acids, replication, translation, and transcription,...

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This lecture discusses the workings of the ribosome. The lecture gives an in-depth view of the structure and function of the ribosome and highlights pioneering efforts over the last 35 years using electron...

This lecture introduces lipids and the cell membrane. Several different lipid structures found in biology are described. Professor Cegelski discusses the supramolecular lipid structures, specifically investigation...

In this lecture, Professor Cegelski introduces and explores the world of carbohydrates. She begins with some explanation of the structure of the sugar monomers and moves on to the polymers. An overview...

In this lecture, Professor Zare discusses kinetics and its relevance to biochemistry. Areas highlighted include the difference between thermodynamics and kinetics, basic equations, enzyme and Michaelis-Menten...

Prof. Zare continues to discuss kinetics. In particular, he reviews enzyme kinetics and the Michaelis-Menten model, discusses how data may be interpreted, explores interpretations of the Michaelis-Menten...

Prof. Cegelski picks up the discussion of enzymatic catalysis. In particular, she discusses how catalysis is proposed to work mechanistically. This includes explaining the examples of serine proteases...

In this lecture, Professor Cegelski explores the structure and function of hemoglobin and myoglobin. In particular, she discusses the cooperativity of hemoglobin and the models of cooperativity. This gives...

Professor Cegelski discusses biochemical regulation in terms of how enzymes are controlled. First, she continues with the discussion of allostery and how it might be used for regulation in ATCase. Then,...

In this lecture, Professor Cegelski discusses membrane channels and pumps. She discusses the possible methods of transport across the membrane, such as diffusion and active transport. Starting with the...

In this lecture, guest speaker Dr. Felisa Wolfe-Simon discusses the potential for living organisms to use alternative elements for electron transport. This includes an exploration of the thermodynamic...

In this lecture, Professor Cegelski discusses signal transduction and circuitry within cells. After touching on general ideas of signal transduction, she explores the example of G-protein coupled receptors...

In this lecture, Prof. Cegelski discusses molecular motors. First, she details the mechanism of ATP synthase using the proton gradient to turn a protein complex and drive conformational changes that allow...

In this lecture, Professor Cegelski discusses microbes and strategies that are taken to combat bacterial disease. This includes a detailed look at antibiotic mechanisms like penicillin, a discussion of...

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